Mar 19, · In men determined to have androgen deficiency, we recommend additional diagnostic evaluation to ascertain the cause of androgen deficiency. We recommend against starting T therapy in patients who are planning fertility in the near term or have any of a number of specified conditions. Treating Hypogonadism and Your Fertility For men who have hypogonadism, the big question is will they be able to impregnate their partner. Some types of hypogonadism can be treated with TRT (testosterone replacement therapy) and PRT (pituitary hormone therapy). TRT can restore a man’s sexual function as well as increase energy and sex drive.